The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2024
Filed:
Jul. 06, 2021
Applicant:
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Muthiah Manoharan, Cambridge, MA (US);
Kallanthottathil G. Rajeev, Cambridge, MA (US);
Jayaprakash K. Nair, Cambridge, MA (US);
Martin Maier, Cambridge, MA (US);
Assignee:
ALNYLAM PHARMACEUTICALS, INC., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7004 (2006.01); A61K 31/70 (2006.01); A61K 31/7052 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 47/16 (2006.01); A61K 47/22 (2006.01); A61K 47/28 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); C07H 21/02 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/28 (2013.01); A61K 31/70 (2013.01); A61K 31/7004 (2013.01); A61K 31/7052 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/16 (2013.01); A61K 47/22 (2013.01); A61K 47/543 (2017.08); A61K 47/549 (2017.08); A61K 47/60 (2017.08); C07H 21/02 (2013.01); A61K 48/00 (2013.01); Y02A 50/30 (2018.01); Y02P 20/55 (2015.11);
Abstract
The present invention provides a phosphorothioate-modified oligonucleotide comprising a structure shown below: The present invention also provides a phosphorothioate-modified oligonucleotide comprising a structure having formula (CIII):