The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2024

Filed:

Dec. 21, 2021
Applicant:

Nykode Therapeutics Asa, Oslo, NO;

Inventors:

Stine Granum, Oslo, NO;

Elisabeth Stubsrud, Oslo, NO;

Agnete Brunsvik Fredriksen, Rælingen, NO;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61P 35/00 (2018.01); A61K 2039/53 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6056 (2013.01); A61K 2039/627 (2013.01); A61K 2039/64 (2013.01); A61K 2039/70 (2013.01);
Abstract

The present invention relates to an anticancer vaccine which includes polynucleotides or polypeptides, methods of treatment of cancer wherein such an anticancer vaccine is used as well as methods for producing the vaccine. The vaccine includes a polynucleotide with a nucleotide sequence encoding a targeting unit, a dimerization unit, a first linker and an antigenic unit. The antigenic unit includes from 3 to 50 antigenic subunits separated by a second linker with each antigenic subunit having at least a part of a cancer neoepitope sequence. The vaccine can include a polypeptide encoded by the polynucleotide or a dimeric protein with two polypeptides encoded by the polynucleotide.


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