The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2024

Filed:

Sep. 23, 2021
Applicant:

Qingdao Haier Biotech Co., Ltd, Qingdao, CN;

Inventors:

Qilong Cao, Qingdao, CN;

Fei Wang, Qingdao, CN;

Hui Li, Qingdao, CN;

Guohu Di, Qingdao, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); A61K 9/00 (2006.01); A61K 35/28 (2015.01); A61K 47/18 (2017.01); A61K 47/24 (2006.01); A61K 47/36 (2006.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 9/0048 (2013.01); A61K 47/186 (2013.01); A61K 47/24 (2013.01); A61K 47/36 (2013.01); C12N 5/0667 (2013.01); C12N 2509/00 (2013.01);
Abstract

The present disclosure relates to an eyedrop applicable to limbal stem cell deficiency and a preparation method, wherein each liter of the eyedrop includes the following components: 1 to 40 mg of human adipose-derived stem cell exosomes, excipients: 0.5 to 2 g of sodium hyaluronate, 0.5 to 3 g of vitamin B6 and 0.05 to 0.3 g of benzalkonium chloride, and the balance of medical normal saline, a pH of the eyedrop is 6.5 to 7.5; and the eyedrop of the present disclosure is effective in treating limbal stem cell deficiency.


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