The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2024

Filed:

Dec. 03, 2018
Applicants:

The Regents of the University of California, Oakland, CA (US);

Niren Murthy, Berkeley, CA (US);

Joachim Justad Roeise, Berkeley, CA (US);

Chung Hak Taing, Berkeley, CA (US);

Inventors:

Niren Murthy, Berkeley, CA (US);

Joachim Justad Roeise, Berkeley, CA (US);

Chung Hak Taing, Berkeley, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4192 (2006.01); A61K 31/192 (2006.01); A61K 38/46 (2006.01); A61K 47/61 (2017.01);
U.S. Cl.
CPC ...
A61K 31/4192 (2013.01); A61K 31/192 (2013.01); A61K 38/465 (2013.01); A61K 47/61 (2017.08);
Abstract

The present disclosure provides endosomal disruptors, which are useful for facilitating delivery of a macromolecule to the cytoplasm of a cell. The present disclosure provides compositions comprising an endosomal disruptor and a macromolecule. The present disclosure provides methods of delivering a macromolecule to the cytoplasm of a cell.


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