The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2024

Filed:

Mar. 05, 2020
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Qiao Lin, New York, NY (US);

Yibo Zhu, New York, NY (US);

Junyi Shang, New York, NY (US);

Zhixing Zhang, New York, NY (US);

Xuejun Wang, New York, NY (US);

Jaeyoung Yang, New York, NY (US);

Cheng Wang, New York, NY (US);

Zhuang Hao, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 5/1477 (2006.01); A61B 5/1491 (2006.01); G01N 27/414 (2006.01); G01N 33/74 (2006.01); H01L 21/02 (2006.01); H01L 23/38 (2006.01); H01L 29/16 (2006.01); H10K 10/46 (2023.01); H10K 85/20 (2023.01);
U.S. Cl.
CPC ...
A61B 5/14532 (2013.01); A61B 5/14507 (2013.01); A61B 5/14539 (2013.01); A61B 5/14546 (2013.01); A61B 5/1477 (2013.01); A61B 5/1491 (2013.01); A61B 5/6821 (2013.01); G01N 27/4145 (2013.01); G01N 27/4146 (2013.01); G01N 33/74 (2013.01); H01L 21/02425 (2013.01); H01L 21/02527 (2013.01); H01L 21/0262 (2013.01); H01L 21/02664 (2013.01); H01L 23/38 (2013.01); H01L 29/1606 (2013.01); H10K 10/484 (2023.02); G01N 2333/62 (2013.01); H10K 85/20 (2023.02);
Abstract

A microdevice for monitoring a target analyte is provided. The microdevice can include a field effect transistor comprising a substrate, a gate electrode, and a microfluidic channel including graphene. The microfluidic channel can be formed between drain electrodes and source electrodes on the substrate. The microdevice can also include at least one aptamer functionalized on a surface of the graphene. The at least one aptamer can be adapted for binding to the target analyte. Binding of the target analyte to the at least one aptamer can alter the conductance of the graphene.


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