The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
May. 15, 2023
Applicants:
Trustees of Boston University, Boston, MA (US);
Northwestern University, Evanston, IL (US);
Inventors:
Ji-Xin Cheng, Newton, MA (US);
Junjie Li, Arlington, MA (US);
Yuying Tan, Allston, MA (US);
Daniela Matei, Chicago, IL (US);
Guangyuan Zhao, Chicago, IL (US);
Assignees:
Trustees of Boston University, Boston, MA (US);
Northwestern University, Evanston, IL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01J 3/44 (2006.01); G01N 27/30 (2006.01); G01N 27/416 (2006.01); G01N 33/487 (2006.01); G01N 33/49 (2006.01); G01Q 60/60 (2010.01); G16H 20/10 (2018.01); G16H 50/30 (2018.01); G01N 21/65 (2006.01);
U.S. Cl.
CPC ...
G01N 33/492 (2013.01); G01N 27/30 (2013.01); G01N 27/416 (2013.01); G01N 33/48735 (2013.01); G01Q 60/60 (2013.01); G16H 20/10 (2018.01); G16H 50/30 (2018.01); G01N 21/65 (2013.01); G01N 2800/52 (2013.01);
Abstract
Disclosed is an assay for determining resistance in a target cell or tissue to a therapy associated with cellular stress using chemical microscopy and high-throughput single cell analysis to determine functional metabolic alteration, including determining metabolic reprogramming in a target cell or tissue to a therapy associated with cellular stress, and methods of using the assays.