The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Oct. 28, 2021
Applicant:
Children's Medical Center Corporation, Boston, MA (US);
Inventors:
Derrick James Rossi, Roslindale, MA (US);
Luigi Warren, Brookline, MA (US);
Assignee:
Children's Medical Center Corporation, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C07K 14/435 (2006.01); C12N 5/074 (2010.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C07K 14/435 (2013.01); C12N 15/11 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01);
Abstract
Described herein are synthetic, modified RNAs for changing the phenotype of a cell, such as expressing a polypeptide or altering the developmental potential. Accordingly, provided herein are compositions, methods, and kits comprising synthetic, modified RNAs for changing the phenotype of a cell or cells. These methods, compositions, and kits comprising synthetic, modified RNAs can be used either to express a desired protein in a cell or tissue, or to change the differentiated phenotype of a cell to that of another, desired cell type.