The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Feb. 11, 2022
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Quinn P. Peterson, Cambridge, MA (US);

Felicia J. Pagliuca, Cambridge, MA (US);

Douglas A. Melton, Cambridge, MA (US);

Jeffrey Robert Millman, Cambridge, MA (US);

Michael Saris Segel, Cambridge, MA (US);

Mads Gurtler, Cambridge, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 35/39 (2015.01); A61P 3/10 (2006.01); A61P 5/48 (2006.01); A61P 5/50 (2006.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0678 (2013.01); A61K 35/39 (2013.01); A61P 3/10 (2018.01); A61P 5/48 (2018.01); A61P 5/50 (2018.01); C12N 5/0606 (2013.01); C12N 5/0676 (2013.01); C12N 5/0696 (2013.01); C12N 2501/11 (2013.01); C12N 2501/117 (2013.01); C12N 2501/15 (2013.01); C12N 2501/16 (2013.01); C12N 2501/375 (2013.01); C12N 2501/385 (2013.01); C12N 2501/395 (2013.01); C12N 2501/40 (2013.01); C12N 2501/41 (2013.01); C12N 2501/727 (2013.01); C12N 2501/998 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01); C12N 2506/03 (2013.01); C12N 2506/22 (2013.01); C12N 2506/45 (2013.01);
Abstract

Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.


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