The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Dec. 10, 2018
Applicant:

Pioneer Hi-bred International, Inc., Johnston, IA (US);

Inventors:

Ute Baumann, Glen Osmond, AU;

Andrew Mark Cigan, Madison, WI (US);

Margaret Anne Pallotta, Norwood, AU;

Manjit Singh, Johnston, IA (US);

Radoslaw Suchecki, Pasadena, AU;

Nathan Spencer Watson-Haigh, Novar Gardens, AU;

Ryan Whitford, Eastwood, AU;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8289 (2013.01); C07K 14/415 (2013.01); C12N 15/8213 (2013.01);
Abstract

Compositions and methods are provided for genome modification of a nucleotide sequence located in or near a male fertility gene of Ms1 or Ms5 in the genome of a plant cell or plant to produce a male-sterile plant. In some examples, the methods and compositions employ a guide RNA/Cas endonuclease system for modifying or altering target sites located in or near a male fertility gene of Ms1 or Ms5 in the genome of a plant cell, plant or seed to produce a male-sterile plant. Also provided are compositions and methods employing a guide polynucleotide/Cas endonuclease system for genome modification a nucleotide sequence located in or near a male fertility gene of Ms1 or Ms5 in the genome of a plant cell to produce a male-sterile plant. Compositions and methods are also provided for restoring fertility to a Ms1 or Ms5 nucleotide sequence to a male-sterile Ms1 or Ms5 plant produced using the methods and compositions described herein.


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