The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Jun. 10, 2020
Applicants:
Biontech SE, Mainz, DE;
Tron—translationale Onkologie an Der Universitätsmedizin Der Johannes Gutenberg—universität Mainz Gg, Mainz, DE;
Inventors:
Florian Eberle, Tübingen, DE;
Ugur Sahin, Mainz, DE;
Andreas Kuhn, Mainz, DE;
Britta Vallazza, Darmstadt, DE;
Mustafa Diken, Mainz, DE;
Assignees:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61K 39/00 (2006.01); A61K 48/00 (2006.01); C12N 15/67 (2006.01); C12N 15/68 (2006.01); C12N 15/70 (2006.01); C12N 15/85 (2006.01); C12P 19/34 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/68 (2013.01); A61K 39/00 (2013.01); A61K 48/0066 (2013.01); C12N 15/67 (2013.01); C12N 15/70 (2013.01); C12N 15/85 (2013.01); C12P 19/34 (2013.01); C12P 21/00 (2013.01); A61K 2039/53 (2013.01); C12N 2830/50 (2013.01);
Abstract
The present invention relates to nucleic acid molecules containing poly (dA:dT) regions which are stabilized in.-, methods of propagating such nucleic acid molecules in, methods of obtaining RNA, peptides or proteins using such nucleic acid molecules and to RNA which is obtained from such nucleic acid molecules and its use. In particular, the poly (dA:dT) regions contain at least one disruption by a sequence not encoding a sequence solely composed of A residues.