The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Apr. 28, 2017
The Provost, Fellows, Foundation Scholars, & the Other Members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth Neard Dublin, Dublin, IE;
Imperial College Innovations Limited, London, GB;
Duke University, Durham, NC (US);
Peter Humphries, Dublin, IE;
Marian Humphries, Dublin, IE;
Matthew Campbell, Dublin, IE;
Anna-Sophia Kiang, Bray, IE;
Daniel Stamer, Durham, NC (US);
Darryl Ray Overby, London, GB;
Chi Shing Lawrence Tam, Dublin, IE;
PROV FELLOWS COLLEGE HOLY TRINITY QUEEN ELIZABETH, Dublin, IE;
IMPERIAL COLLEGE INNOVATIONS LIMITED, London, GB;
DUKE UNIVERSITY, Durham, NC (US);
Abstract
The present invention is directed to an RNAi-inducing agent capable of reducing and/or inhibiting the expression of proteins associated with the tight junction complex joining Schlemm's canal endothelial cells (SCEC) in the eye of a subject for use in the prevention and/or treatment of glaucoma. Specifically, the RNAi-inducing agent is capable of reducing and/or inhibiting the expression of proteins expressed in the tight junction complex or supporting the tight junction complex joining Schlemm's canal endothelial cells (SCEC) in the eye of a subject for use in the prevention and/or treatment of glaucoma. Methods using this RNAi-inducing agent are also contemplated.