The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Dec. 07, 2020
Applicant:
Sirnaomics, Inc., Gatithersburg, MD (US);
Inventors:
Xiaoyong Lu, Gaithersburg, MD (US);
Patrick Y. Lu, Gaithersburg, MD (US);
David M. Evans, Gaithersburg, MD (US);
Assignee:
Sirnaomics, Inc., Germantown, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 47/64 (2017.01); C07K 7/06 (2006.01); C12N 15/113 (2010.01); C12N 15/117 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 47/64 (2017.08); C07K 7/08 (2013.01); C12N 15/117 (2013.01); C07K 7/06 (2013.01); C12N 2310/11 (2013.01); C12N 2310/127 (2013.01); C12N 2310/13 (2013.01); C12N 2310/141 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3513 (2013.01);
Abstract
Peptide docking vehicle compositions containing a therapeutic compound, such as an siRNA molecule, and a targeting ligand are provided, together with methods for their preparation and use. The compositions and methods allow targeted cell/tissue delivery of the therapeutic compound to a subject by linking a targeting ligand to the compound to provide enhanced therapeutic benefit. The subject may be an animal or a human.