The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Sep. 16, 2020
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventor:

Tingting Jiang, San Diego, CA (US);

Assignee:

ILLUMINA, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 35/13 (2015.01); C07K 16/28 (2006.01); C12N 15/10 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); A61K 35/13 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C12N 15/1003 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6886 (2013.01);
Abstract

Methods and systems are provided for differentiating between cancer variants and somatic variants originating from hematopoietic cells in a cell free DNA sample. In some embodiments, the cancer variants can be distinguished from somatic variants originating from hematopoietic cells based on fragment size distribution.


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