The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Jul. 01, 2021
Applicant:

Sanofi, Paris, FR;

Inventors:

Mark Sommerfeld, Frankfurt am Main, DE;

Thomas Langer, Frankfurt am Main, DE;

Uwe Schwahn, Frankfurt am Main, DE;

Werner Dittrich, Frankfurt am Main, DE;

Christine Rudolph, Frankfurt am Main, DE;

Matthias Dreyer, Frankfurt am Main, DE;

Soraya Hölper, Frankfurt am Main, DE;

Christian Lange, Frankfurt am Main, DE;

Katrin Lorenz, Frankfurt am Main, DE;

Assignee:

SANOFI, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/62 (2017.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 47/62 (2017.08); A61K 47/6849 (2017.08); A61K 47/6871 (2017.08); C07K 16/40 (2013.01); C07K 2317/35 (2013.01); C07K 2317/565 (2013.01);
Abstract

Provided herein are FGFR1/KLB targeting agonistic antigen-binding proteins, or fragments thereof, having improved physico-chemical properties. Also provided herein are conjugates comprising an FGFR1/KLB targeting agonistic antigen-binding protein, or a fragment thereof, and at least one GLP-1R agonistic peptide. Further provided are pharmaceutical compositions comprising the antibody (or fragment thereof), or the conjugate provided herein, and the use of the antibody (or fragment thereof), or the use of the conjugate in medicine.


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