The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Mar. 13, 2019
Applicant:
Smivet B.v., Wijchen, NL;
Inventors:
Abraham Johannes de Smit, Wijchen, NL;
Michaël Marie Harmsen, Weesp, NL;
Assignee:
Smivet B.V., Wijchen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); C07K 16/18 (2006.01); C07K 16/42 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1282 (2013.01); C07K 16/18 (2013.01); C07K 16/4283 (2013.01); C07K 2317/22 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/35 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present invention relates to single domain antibodies (SDAs) that are capable of binding to tetanus neurotoxin. The invention further relates to polypeptide constructs comprising such an SDA as well as an SDA that is capable of binding to a serum protein, preferably to serum albumin or immunoglobulin. The invention also relates to nucleic acids encoding such SDAs or polypeptide constructs, to pharmaceutical compositions comprising such SDAs or polypeptide constructs, the medical use thereof and to their use in the treatment of tetanus.