The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Aug. 11, 2022
Uwm Research Foundation, Inc., Milwaukee, WI (US);
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Alexander E. Arnold, Milwaukee, WI (US);
Douglas C. Stafford, Stoughton, WI (US);
James M. Cook, Milwaukee, WI (US);
Charles W. Emala, Woodcliff Lake, NJ (US);
Gloria Forkuo, Milwaukee, WI (US);
Rajwana Jahan, Milwaukee, WI (US);
Revathi Kodali, Milwaukee, WI (US);
Guanguan Li, Milwaukee, WI (US);
Michael Rajesh Stephen, Milwaukee, WI (US);
UWM Research Foundation, Inc., Milwaukee, WI (US);
The Trustees of Columbia University in the City of New York, New York, NY (US);
Abstract
The present invention describes substituted benzo[f]imidazo[1,5-a][1,4]diazepines of the formula (I): wherein R, R, R, R, and X are as disclosed herein. These compounds target alpha-4 and alpha-5 GABAa receptors and are useful for the treatment of airway hyperresponsiveness and inflammation in asthma.