The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Sep. 04, 2020
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Sunitha Nagrath, Ann Arbor, MI (US);

Tae Hyun Kim, Pasadena, CA (US);

Daniel F. Hayes, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/36 (2006.01); A61K 31/727 (2006.01);
U.S. Cl.
CPC ...
A61M 1/362 (2014.02); A61K 31/727 (2013.01); A61M 1/367 (2013.01); A61M 1/3672 (2013.01); A61M 2205/3303 (2013.01); A61M 2205/3306 (2013.01); A61M 2205/3317 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/3337 (2013.01); A61M 2205/50 (2013.01); A61M 2209/088 (2013.01);
Abstract

An apparatus for capturing circulating tumor cells (CTCs) from blood. The apparatus includes a wearable device that receives fluid from vasculature of a subject through an input channel. A pump is coupled to the input channel the pump configured to receive blood at a first flow rate and to convert the flow of the blood to a second flow rate. The device further includes a replaceable candidate cell capture module having a microfluidic capture stage with herringbone channel structures configured to capture the candidate cells by antibodies. The device is further configured to provide the blood back to the vasculature of the subject.


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