The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Aug. 05, 2021
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Paul Carter, Hillsborough, CA (US);

Christoph Spiess, Mountain View, CA (US);

Yiyuan Yin, Fremont, CA (US);

Jianhui Zhou, Redwood City, CA (US);

Wendy Sandoval, San Bruno, CA (US);

Jacob Corn, Berkeley, CA (US);

Michael Dillon, San Francisco, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 39/395 (2006.01); A61K 39/44 (2006.01); C07K 16/46 (2006.01); G16B 20/30 (2019.01); G16B 20/50 (2019.01); A61K 39/00 (2006.01); G01N 33/68 (2006.01); G16B 5/00 (2019.01); G16B 20/00 (2019.01);
U.S. Cl.
CPC ...
A61K 39/44 (2013.01); A61K 39/39558 (2013.01); C07K 16/468 (2013.01); G16B 20/30 (2019.02); G16B 20/50 (2019.02); A61K 39/3955 (2013.01); A61K 39/39566 (2013.01); A61K 2039/507 (2013.01); C07K 2317/31 (2013.01); C07K 2317/522 (2013.01); C07K 2317/56 (2013.01); G01N 33/6848 (2013.01); G16B 5/00 (2019.02); G16B 20/00 (2019.02);
Abstract

Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.


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