The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Jul. 15, 2019
Applicant:

Valneva SE, Saint-Herblain, FR;

Inventors:

Luc Batard, Saint-Herblain, FR;

Caroline Freslon-Evain, Orvault, FR;

Fabien Perugi, Nantes, FR;

Klaus Schwamborn, Nantes, FR;

Assignee:

Valneva SE, Nantes, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/17 (2006.01); A61K 39/39 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/17 (2013.01); A61K 39/39 (2013.01); C12N 7/00 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/6043 (2013.01); C12N 2760/18134 (2013.01); C12N 2760/18334 (2013.01); C12N 2760/18534 (2013.01);
Abstract

The present invention relates to methods of rescue and/or propagation of paramyxovirus species, particularly wherein both rescue and propagation are carried out in the same cell type; i.e., without the use of helper cells for viral rescue. The paramyxoviruses produced by the disclosed methods may encompass wild-type viruses, chimeric viruses, recombinant viruses or engineered viral products such as virus like particles (VLP). Viruses and/or viral products produced in the method according to the current invention are suitable for medical or veterinary use in such applications as treating or preventing infectious diseases, particularly avian paramyxovirus and human respiratory virus infections, and cancer treatment.


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