The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Dec. 05, 2017
Nantbio, Inc., Culver City, CA (US);
Nant Holdings Ip, Llc, Culver City, CA (US);
Nantomics, Llc, Culver City, CA (US);
Kayvan Niazi, Culver City, CA (US);
Nicholas J. Witchey, Culver City, CA (US);
Stephen Charles Benz, Culver City, CA (US);
Shahrooz Rabizadeh, Culver City, CA (US);
NantBio, Inc., Culver City, CA (US);
Nant Holdings IP, LLC, Culver City, CA (US);
NantOmics, LLC, Culver City, CA (US);
Abstract
The invention provides a method of validating the therapeutic composition that is prepared for immunotherapy of a tumor or cancer. The method includes, triggering of an immune response to a neoepitope of a subject's tumor by: a) obtaining neoepitope sequence data from the tumor of a subject; b) obtaining immune competent cells; c) using the neoepitope sequence data to generate a neoepitope presentation system; d) triggering an immune response by contacting the immune competent cells with the neoepitope presentation system; and e) quantifying the triggering of the immune response from the contacted immune competent cells.