The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Jan. 31, 2019
Applicant:
The Royal Institution for the Advancement of Learning / Mcgill University, Montreal, CA;
Inventors:
Siegfried Hekimi, Montreal, CA;
Ying Wang, Montreal, CA;
Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); A61K 9/107 (2006.01); A61K 31/122 (2006.01); A61K 31/337 (2006.01); A61K 38/13 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 31/122 (2013.01); A61K 9/107 (2013.01); A61K 31/337 (2013.01); A61K 47/42 (2013.01);
Abstract
The present disclosure concerns methods and formulations for delivery of hydrophobic agents (such as ubiquinone or poorly soluble drugs) for therapeutic and bioanalytical use. It further concerns use of lipopeptides (e.g. caspofungin) or surfactants to solubilize hydrophobic agents and thus increase their bioavailability. Also described are therapeutic methods for the treatment of conditions that benefit from such hydrophobic agents. The present disclosure further relates to methods of identifying drug candidates for treatment of ubiquinone deficiency.