The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2024
Filed:
Jun. 11, 2019
Applicant:
Accuragen Holdings Limited, Grand Cayman, KY;
Inventors:
Li Weng, Fremont, CA (US);
Malek Faham, Burlingame, CA (US);
Assignee:
ACCURAGEN HOLDINGS LIMITED, George Town, KY;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); C12Q 1/6855 (2018.01); C12Q 1/6874 (2018.01); C12Q 1/6876 (2018.01); C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12Q 1/6855 (2013.01); C12Q 1/6874 (2013.01); C12Q 1/6876 (2013.01); C12Q 1/34 (2013.01);
Abstract
In some aspects, the present disclosure provides methods for forming ligation products comprising single-stranded polynucleotides without the need for enriching the single-stranded polynucleotides. Ligation products formed by various aspects of the present disclosure can be useful for various applications, including but not limited to sequence analysis. In some embodiments, the ligation products comprise cell-free polynucleotides. In some aspects, the present disclosure provides reaction mixtures, kits and complexes consistent with the methods herein.