The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2024

Filed:

Sep. 29, 2017
Applicants:

Kmetijski In{hacek Over (S)}titut Slovenije, Ljubljana, SI;

Univerza V Ljubljani, Ljubljana, SI;

Inventors:

Anastasija Panevska, Sofija, BG;

Jaka Razinger, Ljubljana, SI;

Kristina Sep{hacek over (c)}ić, Ljubljana, SI;

Peter Ma{hacek over (c)}ek, Brezovica, SI;

Matej Sko{hacek over (c)}aj, Materija, SI;

{hacek over (S)}pela Modic, Ljubljana, SI;

Maru{hacek over (s)}a Novak, Kr{hacek over (s)}ko, SI;

Matej Butala, Ljubljana, SI;

Vesna Hodnik, {hacek over (Z)}abnica, SI;

Maja Grundner, Ljubljana, SI;

Tom Turk, Ljubljana-{hacek over (S)}martno, SI;

Assignees:

KMETIJSKI INSTITUT SLOVENIJE, Ljubljana, SI;

Univerza v Ljubljani, Ljubljana, SI;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/50 (2020.01); C07K 14/375 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8286 (2013.01); A01N 63/50 (2020.01); C07K 14/375 (2013.01);
Abstract

The present invention relates to cytolytic bi-component protein complexes consisting of a plurality of molecules of a member of the aegerolysin family and a plurality of molecules of a member of the MACPF superfamily, and particularly to their use for controlling a plant pest, such as for controlling Colorado potato beetle () or Western corn rootworm (). More specifically, the invention relates to cytolytic bi-component protein complexes formed by a plurality of molecules of one of the aegerolysins ostreolysin A6 (OlyA6), pleurotolysin A2 (PlyA2) and erylysin A (EryA) with a plurality of molecules of pleurotolysin B (PlyB) or similar proteins, which have been shown to be toxic for the aforementioned agricultural pest insects.


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