The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2024
Filed:
Dec. 03, 2019
Applicant:
Crown Laboratories, Inc., Johnson City, TN (US);
Inventors:
Thomas Hitchcock, Dallas, TX (US);
Mun Su Rhee, Johnson City, TN (US);
Assignee:
Crown Laboratories, Inc., Johnson City, TN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/21 (2006.01); C07K 14/475 (2006.01); C07K 14/54 (2006.01); C07K 14/715 (2006.01); C12N 15/74 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/746 (2013.01); C07K 14/475 (2013.01); C07K 14/715 (2013.01); A61K 48/0025 (2013.01);
Abstract
Microbes can be genetically modified to express biomolecules that are beneficial to mammals and/or to reduce, or eliminate, expression of harmful virulence factors. The growth and viability of such genetically modified microbes can optionally be controlled by inducible promoters that regulate the expression of proteins that are essential to their growth and survival. Compositions comprising such genetically modified microbes as well as methods of making and using the same are disclosed herein.