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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12049625 B1

PDFFull Text
Date of Patent:
Jul. 30, 2024

Filed:

Jan. 13, 2017

Genome editing for treating glioblastoma

Applicant:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

Anna M. Krichevsky, Brookline, MA (US);

Rachid El-Fatimy, Brighton, MA (US);

Erik J. Uhlmann, Newton Center, MA (US);

Assignee:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Michael D Burkhart

Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 9/00 (2006.01); A61K 31/7088 (2006.01); A61K 38/46 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C12N 9/22 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/0019 (2013.01); A61K 9/0085 (2013.01); A61K 31/7088 (2013.01); A61K 38/465 (2013.01); A61K 48/0066 (2013.01); A61P 35/00 (2018.01); C12N 9/22 (2013.01); C12N 2310/113 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01); C12Q 1/6886 (2013.01);
Abstract

A method of treating a subject who has a glioma, e.g., astrocytoma, oligodendroglioma, or glioblastoma multiforme tumor, the method comprising administering to the subject a therapeutically effective amount of a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) microRNA-10b (miR-10b) editing complex comprising a CRISPR Associated Protein 9 (Cas9) and at least one guide RNA targeting a sequence encoding miR-10b.

Find Patent Forward Citations

Krichevsky, Anna. (2024). Genome editing for treating glioblastoma (U.S. Patent No. 12049625). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12049625

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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