The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2024

Filed:

Sep. 10, 2019
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Artaches Kazarian, Belmont, MA (US);

Wesley Barnhart, Newbury Park, CA (US);

Iain David Grant Campuzano, Thousand Oaks, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/16 (2006.01); B01D 15/36 (2006.01); B01J 41/20 (2006.01); C12N 15/10 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/101 (2013.01); B01D 15/166 (2013.01); B01D 15/363 (2013.01); B01J 41/20 (2013.01); C12N 15/111 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3231 (2013.01);
Abstract

The present invention relates to methods for purifying nucleic acids. In particular, the present invention relates to a method for separating guanine-rich oligonucleotides from quadruplex secondary structures formed from the oligonucleotides using monolithic anion exchange chromatography. Mobile phase parameters that control quadruplex formation and enable separation of the intact quadruplex from the single-strand oligonucleotide are also described.


Find Patent Forward Citations

Kazarian, Artaches. (2024). Purification methods for guanine-rich oligonucleotides (U.S. Patent No. 12049620). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12049620

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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