The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2024
Filed:
Aug. 05, 2022
Industry Academic Cooperation Foundation, Hallym University, Chuncheon-si, KR;
Chan Hum Park, Chuncheon-si, KR;
Young Jin Lee, Seosan-si, KR;
Olatunji Abolarin Ajiteru, Chuncheon-si, KR;
Ok Joo Lee, Chuncheon-si, KR;
Ji Seung Lee, Bucheon-si, KR;
Han Na Lee, Chuncheon-si, KR;
Md Tipu Sultan, Chuncheon-si, KR;
Jang Min Kim, Chuncheon-si, KR;
Oh Jun Kwon, Namyangju-si, KR;
Ji Ye Kim, Wonju-si, KR;
Ji Won Heo, Chuncheon-si, KR;
Soon Hee Kim, Chuncheon-si, KR;
INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY, Chuncheon-si, KR;
Abstract
The present disclosure relates to the composition and process for the production of an ultra-strong, biocompatible, electroconductive, and stretchable hydrogel, which comprises: a step (a) of physical or chemical modification of natural polymers e.g., preparation of silk nanofiber and double methacrylation of gelatin; a step (b) of graphene oxide (GO) carboxylation; a step (c) of carbodiimidation between methacrylated natural polymers of step (a) and carboxylated GO of step (b); and a step (d) of three dimensional (3D) bioprinting of step (c) with/without silk nanofiber. It was found that these steps in this disclosure give rise to a biocompatible hydrogel with high mechanical strength in the range of load-bearing soft tissue such as tendon and heart as opposed to conventional hydrogels.