The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2024

Filed:

Jan. 18, 2018
Applicant:

Crestecbio Inc., Ibaraki, JP;

Inventors:

Yukio Nagasaki, Ibaraki, JP;

Takuya Inagaki, Ibaraki, JP;

Binh Long Vong, Ibaraki, JP;

Assignee:

CrestecBio Inc., Ibaraki, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 81/02 (2006.01); A61K 9/107 (2006.01); A61K 9/51 (2006.01); A61K 31/44 (2006.01); A61K 31/4709 (2006.01); A61K 31/785 (2006.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
C08G 81/025 (2013.01); A61K 9/1075 (2013.01); A61K 9/5115 (2013.01); A61K 31/44 (2013.01); A61K 31/4709 (2013.01); A61K 31/785 (2013.01); A61K 47/34 (2013.01);
Abstract

A copolymer which includes hydrophilic and hydrophobic blocks, which can form nanoparticles in which a physiologically active substance can be efficiently packaged therein and which are stable under acidic conditions. The hydrophilic segment of the copolymer is composed of polyethylene glycol (PEG) and the hydrophobic segment is composed of polystyrene. The hydrophobic segment has a side chain, and the side chain has ends to which a cyclic nitroxide radical having a radical scavenging function and a trialkoxysilane are covalently bonded.


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