The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2024

Filed:

Mar. 09, 2020
Applicant:

The Queen's University of Belfast, Belfast, GB;

Inventors:

Helen McCarthy, Belfast, GB;

Nicholas Dunne, Belfast, GB;

Tracy Robson, Belfast, GB;

Emma McErlean, Belfast, GB;

Eoghan Mulholland, Belfast, GB;

Grace Cole, Belfast, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61P 35/00 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61P 35/00 (2018.01); C12N 15/87 (2013.01); C07K 2318/20 (2013.01);
Abstract

Provided is a peptide including X-(Xaa1)a-(Xaa2)b-Y-(Xaa3)c-(Xaa4)d-Z, or a salt or amide thereof, in which each of X and Z is independently selected from Asn, Cys, Gln, Gly, Ser, Thr and Tyr; in which one of Xaa1 and Xaa2 is His and the other of Xaa1 and Xaa2 is Arg; in which one of Xaa3 and Xaa4 is His and the other of Xaa3 and Xaa4 is Arg; in which the amino functional group of X is, optionally, acylated; in which the carboxylate functional group of Z is, optionally, amidated; in which Y is selected from Ala and Trp; in which each of a and d is independently an integer from 2 to 4; and each of b and c is independently an integer from 2 to 4. The peptide may be used in therapeutic approaches.


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