The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2024
Filed:
Aug. 04, 2021
Applicant:
Macrogenics, Inc., Rockville, MD (US);
Inventors:
Ling Huang, Bethesda, MD (US);
Leslie S. Johnson, Rockville, MD (US);
Assignee:
MacroGenics, In, Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C03C 17/38 (2006.01); C03C 17/42 (2006.01); C07K 16/32 (2006.01); G02B 5/08 (2006.01); H01L 31/054 (2014.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); C03C 17/38 (2013.01); C03C 17/42 (2013.01); C07K 16/2803 (2013.01); C07K 16/2827 (2013.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); G02B 5/0808 (2013.01); H01L 31/0547 (2014.12); C03C 2217/445 (2013.01); C03C 2217/465 (2013.01); C03C 2217/479 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/52 (2013.01); C07K 2317/56 (2013.01); C07K 2317/71 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01); Y02E 10/52 (2013.01);
Abstract
The present invention relates to CD3-binding molecules capable of binding to human and non-human CD3, and in particular to such molecules that are cross-reactive with CD3 of a non-human mammal (e.g., a cynomolgus monkey). The invention also pertains to uses of such antibodies and antigen-binding fragments in the treatment of cancer, autoimmune and/or inflammatory diseases and other conditions.