The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2024
Filed:
Aug. 11, 2021
Applicant:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Inventors:
Dongfang Liu, Millburn, NJ (US);
Minh Ma, New Brunswick, NJ (US);
Saiaditya Badeti, New Brunswick, NJ (US);
Assignee:
Rutgers, The State University of New Jersey, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 35/15 (2015.01); A61K 35/17 (2015.01); A61K 39/00 (2006.01); A61P 31/14 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 14/725 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61K 35/15 (2013.01); A61K 35/17 (2013.01); A61P 31/14 (2018.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 14/7151 (2013.01); C12N 9/6472 (2013.01); C12Y 304/22062 (2013.01); A61K 39/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/53 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract
Chimeric antigen receptors (CARs) including an antigen binding domain specifically binding to coronavirus spike protein, nucleic acids encoding the CARs, vectors including nucleic acids encoding the CARs, and immune cells expressing the CARs are provided. Methods of treating a subject with coronavirus, including administering to the subject an immune cell expressing a disclosed CAR are also provided.