The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2024
Filed:
May. 04, 2018
Applicant:
Kriptic Pharmaceuticals Limited, Dublin, IE;
Inventors:
Kostantinos (Kostas) Kosmatopoulos, Paris, FR;
Jeanne Menez-Jamet, Montrouge, FR;
Catherine Gallou, Bures-sur-Yvette, ER;
Aude Rougeot, Bourg-la-Reine, FR;
Assignee:
KRIPTIC PHARMACEUTICALS LIMITED, Dublin, IE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A61K 39/001157 (2018.08); C12N 5/0638 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55 (2013.01); A61K 2039/55566 (2013.01);
Abstract
The invention pertains to the use of a tumor vaccine composed of two peptides of nine amino acids—the WT cryptic TERT572 (RLFFYRKSV, SEQ ID No: 1) expressed by tumor cells and its optimized variant TERT572Y (YLFFYRKSV, SEQ ID No: 2)—for treating cancer in a HLA-A*0201-positive patient having a non-immunogenic tumor expressing TERT.