The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2024

Filed:

Aug. 30, 2021
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Brian D. Klein, Potomac, MD (US);

Hilde Lavreysen, Lommel, BE;

Stefan Maria Christiaan Pype, Boechout, BE;

Roy E. Twyman, Doylestown, PA (US);

Nancy Eulalie Sylvain Van Osselaer, Lier, BE;

H. Steven White, Seattle, WA (US);

Marc André Ceusters, Diest, BE;

José Maria Cid-Núñez, Toledo, ES;

Andrés Avelino Trabanco-Suárez, Olias del Rey, ES;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 9/48 (2006.01); A61K 31/381 (2006.01); A61K 31/4015 (2006.01); A61K 31/437 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); A61P 25/02 (2006.01); A61P 25/06 (2006.01); A61P 25/08 (2006.01); A61P 25/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 9/4858 (2013.01); A61K 31/381 (2013.01); A61K 31/4015 (2013.01); A61K 31/437 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 38/1787 (2013.01); A61K 45/06 (2013.01); A61P 25/02 (2018.01); A61P 25/06 (2018.01); A61P 25/08 (2018.01); A61P 25/18 (2018.01);
Abstract

The present invention relates to combinations comprising a positive allosteric modulator ('PAM') of metabotropic glutamatergic receptor subtype 2 (“mGluR2”) or a pharmaceutically acceptable salt or a solvate thereof, or an orthosteric agonist of metabotropic glutamatergic receptor subtype 2 compound or a pharmaceutically acceptable salt or a solvate thereof, and a synaptic vesicle protein 2A (“SV2A”) ligand.


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