The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2024

Filed:

Dec. 21, 2022
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Cheng Frank Zhong, Fremont, CA (US);

Paul Lundquist, San Francisco, CA (US);

Mathieu Foquet, Newark, CA (US);

Jonas Korlach, Camas, WA (US);

Hovig Bayandorian, Berkeley, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6825 (2018.01); C12Q 1/6874 (2018.01); G01N 21/77 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6825 (2013.01); G01N 21/6428 (2013.01); G01N 21/648 (2013.01); G01N 21/7703 (2013.01); G01N 33/54373 (2013.01); G01N 2021/6463 (2013.01); G01N 2201/06113 (2013.01); G01N 2201/0638 (2013.01); G01N 2201/08 (2013.01);
Abstract

This invention provides devices for use in various analytical applications including single-molecule analytical reactions. Methods for detecting analytes optically by propagating optical energy by waveguides within a substrate are provided. Analytical devices are provided which have both shallow and deep waveguides in which illumination light is transported through the deep waveguides and coupled into the shallow waveguides. The shallow waveguides provide evanescent field illumination to analytes, such as single-molecule analytes, within nanometer scale wells. Integrated devices including integrated detectors such as CMOS detectors are included.


Find Patent Forward Citations

Loading…