The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
Mar. 30, 2018
Applicant:
Exothera SA, Charleroi, BE;
Inventors:
José Castillo, Brussels, BE;
Vasily Medvedev, Nivelles, BE;
Assignee:
EXOTHERA SA, Nivelles, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/06 (2006.01); C07K 1/18 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/06 (2013.01); C07K 1/18 (2013.01); C12Q 1/00 (2013.01);
Abstract
The invention provides a method and a kit for combined virus inactivation and capture/purification of a feed containing a protein of interest. The method comprises the steps of: contacting a feed comprising a protein of interest with negatively charged particles or media, conditioning the particles or media such that the pH is acidic thereby inactivating said virus, and eluting said protein of interest.