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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12043848 B1

PDFFull Text
Date of Patent:
Jul. 23, 2024

Filed:

Oct. 16, 2018

Aav vectors

Applicant:

Vigeneron Gmbh, Starnberg, DE;

Inventors:

Stylianos Michalakis, Munich, DE;

Martin Biel, Starnberg, DE;

Christian Schön, Mietingen, DE;

Hildegard Büning, Hannover, DE;

Assignee:

Vigeneron GmbH, Starnberg, DE;

Attorney:

McNeill Baur PLLC

Primary Examiner:

Benjamin P Blumel

Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 48/00 (2006.01); A61K 49/00 (2006.01); C07K 14/005 (2006.01); C12N 15/10 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 48/005 (2013.01); A61K 48/0075 (2013.01); A61K 49/00 (2013.01); C07K 14/005 (2013.01); C12N 15/1082 (2013.01); C12N 15/86 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14145 (2013.01); C12N 2750/14171 (2013.01);
Abstract

The present invention relates to an adeno-associated virus (AAV), comprising an insertion of at least 6-8 amino acids between the positions corresponding to position 587 and 588 of SEQ ID NO: 1. Also envisioned are AAVs of the present invention for use as a medicament and pharmaceutical compositions comprising the AAV of the present invention. Further, the present invention relates to an in vitro use of AAV of the present invention for transduction of the nucleus of retinal cells. Also concerned is a method for screening an insertion sequence as well as a peptide obtainable by the method for screening. Also contemplated are kits comprising the AAV of the present invention.

Find Patent Forward Citations

Michalakis, Stylianos. (2024). Aav vectors (U.S. Patent No. 12043848). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12043848

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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