The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
Jun. 11, 2020
Applicant:
Ncardia B.v., Leiden, NL;
Inventor:
Stefan Robbert Braam, Leiden, NL;
Assignee:
NCARDIA B.V., Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 2500/25 (2013.01); C12N 2500/30 (2013.01); C12N 2500/32 (2013.01); C12N 2500/33 (2013.01); C12N 2500/34 (2013.01); C12N 2500/36 (2013.01); C12N 2500/38 (2013.01); C12N 2500/90 (2013.01); C12N 2501/30 (2013.01); C12N 2501/33 (2013.01); C12N 2501/395 (2013.01); C12N 2501/40 (2013.01); C12N 2501/998 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01);
Abstract
The current disclosure relates to a culture medium, different methods to generate adult-like cardiomyocytes from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC) using the medium, in particular from stem cells that differentiated into (foetal) cardiomyocytes, and to kits comprising the medium, or the medium together with differentiated (foetal) cardiomyocytes derived from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC).