The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
May. 16, 2018
Applicants:
Children's Hospital Medical Center, Cincinnati, OH (US);
Medizinische Hochschule Hannover, Hannover, DE;
Inventors:
Bruce C. Trapnell, Cincinnati, OH (US);
Takuji Suzuki, Tochigi, JP;
Thomas Moritz, Bonn, DE;
Nico Lachmann, Burgdorf, DE;
Axel Schambach, Hannover, DE;
Assignees:
Children's Hospital Medical Center;
Medizinische Hochschule Hannover, Hannover, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/0276 (2024.01); A61K 35/15 (2015.01); A61K 48/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A01K 67/0276 (2013.01); A61K 35/15 (2013.01); A61K 48/0058 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0306 (2013.01); C12N 2740/16043 (2013.01); C12N 2800/22 (2013.01); C12N 2830/008 (2013.01);
Abstract
The disclosure provides compositions and methods for cell therapy of hPAP in humans using gene corrected and in vitro differentiated patient autologous macrophage cells. The disclosure also provides compositions in the form of a cell product and related compositions and methods for making the cell product and for direct pulmonary transplantation of same.