The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
Jun. 04, 2021
Applicant:
Eisai R&d Management Co., Ltd., Tokyo, JP;
Inventors:
Ryan Henry, Milford, MA (US);
Thiwanka Samarakoon, Westwood, MA (US);
Nathan Fishkin, Weymouth, MA (US);
Ping Zhu, Acton, MA (US);
Ermira Pazolli, Wayland, MA (US);
James Palacino, Wellesley, MA (US);
Juan C. Almagro, Cambridge, MA (US);
Assignee:
Eisai R&D Management Co., Ltd., Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 47/60 (2017.01); A61K 47/65 (2017.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 47/60 (2017.08); A61K 47/65 (2017.08); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61P 35/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/92 (2013.01);
Abstract
Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.