The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
Jul. 13, 2021
Applicant:
Askgene Pharma Inc., Camarillo, CA (US);
Inventors:
Yuefeng Lu, Newbury Park, CA (US);
Jian-Feng Lu, Oak Park, CA (US);
Assignee:
AskGene Pharma Inc., Camarillo, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 9/08 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 9/08 (2013.01); A61K 9/19 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01);
Abstract
The present disclosure relates to fusion molecules and chimeric molecules which comprise two components: an Ang-2 antagonist peptide linked to a VEGF-binding moiety. Further disclosed are methods of using said chimeric molecules to treat a patient cancer, proliferative retinopathy, neovascular glaucoma, macular edema, wet age-related macular degeneration (wAMD), macular edema following retinal vein occlusion (RVO), diabetic macular edema (DME), or diabetic retinopathy (DR).