The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2024

Filed:

May. 26, 2021
Applicants:

Innovative Cellular Therapeutics Holdings, Ltd., Grand Cayman, KY;

Innovative Cellular Therapeutics, Inc., Rockville, MD (US);

Inventors:

Lei Xiao, Rockville, MD (US);

Xiaogang Shen, Shanghai, CN;

Wensheng Wang, Shanghai, CN;

Dongqi Chen, Shanghai, CN;

Beibei Jia, Shanghai, CN;

Chengfei Pu, Shanghai, CN;

Le Tian, Rockville, MD (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 35/17 (2015.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 16/40 (2013.01); A61K 38/00 (2013.01); C12Y 406/01002 (2013.01);
Abstract

The present disclosure relates to compositions and methods of treating a subject having digestive tract cancer, the method comprising: administering an effective amount of a composition to the subject, the composition comprising a first population of cells comprising a first CAR binding a first antigen, and a second population of cells comprising a second CAR binding GCC, wherein the first antigen comprises a cell surface molecule of a white blood cell (WBC).


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