The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
Mar. 19, 2021
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Constance L. Cepko, Newton, MA (US);
Wenjun Xiong, Boston, MA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/7115 (2006.01); A61K 38/17 (2006.01); A61K 38/44 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 31/7115 (2013.01); A61K 38/1709 (2013.01); A61K 38/446 (2013.01); A61K 45/06 (2013.01); A61K 48/005 (2013.01); A61K 48/0075 (2013.01); C12N 2750/14143 (2013.01); C12Y 115/01001 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present invention is directed to methods for the treatment or prevention of oxidative stress in a cell, e.g., photoreceptor cell, and methods for the treatment and prevention of disorders associated therewith by the administration of an agent, e.g., a nucleic acid molecule, which increases the expression and/or activity of an antioxidant defense protein.