The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2024

Filed:

Jan. 19, 2023
Applicants:

The Governors of the University of Alberta, Edmonton, CA;

Helmholtz Center for Infection Research, Braunschweig, DE;

Inventors:

Michael Houghton, Danville, CA (US);

Abdolamir Landi, Edmonton, CA;

Carlos A. Guzman, Braunschweig, DE;

Thomas Ebensen, Braunschweig, DE;

Darren Hockman, Edmonton, CA;

John L. Law, Edmonton, CA;

Michael Logan, Edmonton, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/29 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01); A61P 31/14 (2006.01); A61P 37/04 (2006.01); C01F 11/02 (2006.01); C07D 323/00 (2006.01); C07K 14/005 (2006.01); C07K 14/18 (2006.01); C07K 14/28 (2006.01); C07K 14/33 (2006.01); C07K 14/34 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/29 (2013.01); A61K 39/12 (2013.01); A61K 39/39 (2013.01); A61P 31/14 (2018.01); A61P 37/04 (2018.01); C01F 11/02 (2013.01); C07D 323/00 (2013.01); C07K 14/005 (2013.01); C07K 14/18 (2013.01); C07K 14/28 (2013.01); C07K 14/33 (2013.01); C07K 14/34 (2013.01); C12N 15/86 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55588 (2013.01); C12N 2770/24234 (2013.01);
Abstract

The present disclosure provides immunogenic compositions comprising: a) hepatitis C virus (HCV) E1E2 heterodimers, HCV E2, or HCV E1; and b) an adjuvant, where the adjuvant is a cyclic dinucleotide or an archaeosome. The present disclosure provides methods of inducing an immune response in an individual to HCV, the methods comprising administering to an individual an effective amount of an immunogenic composition of the present disclosure.


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