The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
Nov. 10, 2020
Applicants:
Massachusetts Institute of Technology, Cambridge, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Jeremiah A. Johnson, Boston, MA (US);
Hung Vanthanh Nguyen, Braintree, MA (US);
Yivan Jiang, Revere, MA (US);
Alexandre Detappe, Strasbourg, FR;
Michael Agius, Boston, MA (US);
Irene Ghobrial, Boston, MA (US);
XueZhou Wang, Cambridge, MA (US);
Assignees:
Massachusetts Institute of Technology, Cambridge, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/795 (2006.01); A61K 47/55 (2017.01); A61K 47/60 (2017.01); C07D 495/14 (2006.01); C08G 61/08 (2006.01); C08G 65/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/795 (2013.01); A61K 47/55 (2017.08); A61K 47/60 (2017.08); C07D 495/14 (2013.01); C08G 61/08 (2013.01); C08G 65/00 (2013.01);
Abstract
Disclosed multifunctional compounds, conjugates, macromolecules, and polymers that target dysregulated proteins for degradation. Also disclosed are methods of preparation, compositions, kits, and methods of use relating to the degraders.