The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2024
Filed:
Jul. 19, 2021
Applicant:
Spes Pharmaceuticals Inc., North Brunswick, NJ (US);
Inventors:
Jianwei Yu, Plainsboro, NJ (US);
Yulu Wang, Plainsboro, NJ (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/675 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 47/18 (2017.01); A61K 47/40 (2006.01);
U.S. Cl.
CPC ...
A61K 31/675 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 47/183 (2013.01); A61K 47/40 (2013.01);
Abstract
The present application and its embodiments teach stable compositions of fosaprepitant or a pharmaceutically acceptable salt thereof with such compositions lacking polysorbate 80 and containing dual functional excipients of hydrolysis inhibition and solubility enhancement. Further described are methods of preparation of such compositions. Among other advantages of contemplated compositions, fosaprepitant hydrolysis degradation is kept low and the compositions maintain physically and chemically stable for prolonged period.