The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2024

Filed:

Sep. 05, 2019
Applicant:

Yeda Research and Development Co. Ltd., Rehovot, IL;

Inventors:

Asaph Aharoni, Tel-Aviv, IL;

Prashant Sonawane, Rehovot, IL;

Maxim Itkin, Rehovot, IL;

Adam Jozwiak, Rehovot, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01H 6/82 (2018.01); C12N 9/10 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
A01H 6/82 (2018.05); C12N 9/1059 (2013.01); C12N 15/8218 (2013.01); C12N 15/8243 (2013.01); C12N 15/8247 (2013.01);
Abstract

Provided herein are genetically modified cells and genetically modified plants having increased or decreased expression of a cellulose synthase like G (CSLG) enzyme. These cells and plants may have an increased or decreased content a steroidal alkaloid, a steroidal saponin, or a triterpenoid saponin, compared to a corresponding unmodified cell or plant. Also provided herein are methods of producing a steroidal alkaloid, a steroidal saponin, or a triterpenoid saponin in a genetically modified cell, as well as methods of reducing the content of a steroidal alkaloid, a steroidal saponin, or a triterpenoid saponin in a cell of a plant or a plant part, and methods of increasing the content of a steroidal alkaloid, a steroidal saponin, or a triterpenoid saponin in a cell of a plant or a plant part.


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