The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
Oct. 02, 2020
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Diana Darowski, Gerbrunn, DE;
Camille Loise Sophie Delon, Oberengstringen, CH;
Lydia Jasmin Hanisch, Birmensdorf, CH;
Christian Jost, Zurich, CH;
Christian Klein, Bonstetten, CH;
Ekkehard Moessner, Kreuzlingen, CH;
Vesna Pulko, Zurich, CH;
Wei Xu, Urdorf, CH;
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The present invention generally relates to diagnostic assays using cell cultures, in particular to chimeric antigen receptor (CAR) expressing reporter cell assays to analyze samples, in particular patient samples, to diagnose cancer by quantifying the expression of tumor antigens and/or predicting clinical response to cancer immunotherapies. A further aspect of the present invention is to improve safety of e.g., cancer immunotherapies.