The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2024

Filed:

Feb. 09, 2022
Applicant:

Leica Microsystems Cms Gmbh, Wetzlar, DE;

Inventors:

Falk Schlaudraff, Butzbach, DE;

Florian Hoffmann, Giessen, DE;

Christoph Greb, Marburg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/04 (2006.01); G01N 1/28 (2006.01); G06N 20/00 (2019.01); G02B 21/06 (2006.01); G02B 21/26 (2006.01);
U.S. Cl.
CPC ...
G01N 1/286 (2013.01); G06N 20/00 (2019.01); G01N 2001/045 (2013.01); G01N 2001/2886 (2013.01); G02B 21/06 (2013.01); G02B 21/26 (2013.01);
Abstract

A method for obtaining dissectates from a microscopic sample using a laser microdissection system having a laser unit includes: a) at least partially circumcising and releasing from the sample dissectate regions of the sample as the dissectates using laser pulses provided by the laser unit; b) transferring the dissectates, by being released from the sample, along dissectate trajectories into receptacles of a dissectate collection unit; and c) positioning the receptacles of a dissectate collection unit using a positioning unit to collect the dissectates. The positioning of the receptacles of the dissectate collection unit using the positioning unit is automatically performed based on estimates of the dissectate trajectories, the estimates of the dissectate trajectories being obtained in a learning mode, the learning mode including obtaining dissectates by repeatedly performing at least steps a) and b). Parameters of the dissectate trajectories are determined for a plurality of dissectates.


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