The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
Jan. 07, 2020
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Peiman Hematti, Middleton, WI (US);
Debra Bloom, Sun Prairie, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 9/00 (2006.01); A61K 35/17 (2015.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0638 (2013.01); A61K 9/0019 (2013.01); A61K 35/17 (2013.01); C12N 5/0636 (2013.01); A61K 2039/5158 (2013.01); C12N 2501/25 (2013.01); C12N 2501/50 (2013.01); C12N 2501/51 (2013.01); C12N 2501/515 (2013.01); C12N 2501/599 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present disclosure relates to methods, cells, and compositions for preparing T cell populations and compositions for adoptive cell therapy. In particular, provided herein are methods for efficiently expanding and activating T cell populations for genetic engineering and adoptive T cell immunotherapies. Also provided are cells and compositions produced by the methods and methods of their use.