The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2024

Filed:

Jun. 07, 2023
Applicant:

Bioneer Corporation, Daejeon, KR;

Inventors:

Tae-Rim Kim, Daejeon, KR;

Pyoung Oh Yoon, Daejeon, KR;

Youngho Ko, Seoul, KR;

Seon Joo Bae, Chungcheongnam-do, KR;

Han-Oh Park, Sejong-si, KR;

Seung Seob Son, Chungcheongnam-do, KR;

Jun-Hong Park, Daejeon, KR;

Sung-Il Yun, Daejeon, KR;

Assignee:

Bioneer Corporation, Daejeon, KR;

Attorney:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 9/19 (2006.01); A61K 31/713 (2006.01); A61P 11/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); A61K 9/19 (2013.01); A61K 31/713 (2013.01); A61P 11/00 (2018.01); C12N 2310/14 (2013.01); C12N 2310/314 (2013.01); C12N 2310/322 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3515 (2013.01);
Abstract

The present invention relates to a double-stranded oligonucleotide which can highly specifically and efficiently inhibit an amphiregulin expression and, preferably, a double-stranded oligonucleotide comprising a sequence in the form of RNA/RNA, DNA/DNA or DNA/RNA hybrid, a double-stranded oligonucleotide structure comprising the double-stranded oligonucleotide, nanoparticles comprising the double-stranded oligonucleotide structure, and a fibrosis or respiratory disease preventive or therapeutic use thereof.


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